Several news outlets, including Reuters, AP and NBC, are reporting that a condition of reopening travel to the United States may include vaccination against the SARS-COV-2 virus that causes COVID-19. These reports come only ten days after the White House confirmed that the travel bans currently in place for travelers from 33 countries will remain in place in light of concerns over the transmissibility of the Delta variant. The Biden administration has a keen interest in lifting the travel restrictions; a move expected to jumpstart a lagging economy, but at what cost, both politically and in terms of public health? We are likely to hear more about this developing issue in the coming weeks.